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Dr. Oyepata Simeon Joseph

Reader / Associate Professor | Head of Department

Faculty of Pharmacy · Department of Pharmacology and Toxicology

Specialization Pharmacology, clinical pharmacology and toxicology

Office: Federal University, Oye–Ekiti

Phone: 08038248352

Email: oyepata.joseph@fuoye.edu.ng

Biography

Philosopher, scientist pharmacist pharmacologist and toxicologist

Research Interests

Philosopher, scientist pharmacist pharmacologist and toxicologist

Qualifications

Selected Publications

  1. Evaluation of effect of Pterocarpus santalinus leaf extract on feed consumption, hematological and kidney indices of Wistar rats.
    Authors: Adekunle, A. T., Akeem, A. A., Egbon, O. T., Sabastine, Z. A., Simeon, J. O., & Tosin, J. O.
    Caliphate Journal of Science and Technology (2026)
  2. COVID-19 immunological consequences: immunological significance of viro-allergy-hygiene hypothesis
    Authors: Joseph, O. S.
    Expert Review of Clinical Immunology (2026)
  3. Evaluation of gc-ms profile and anti-inflammatory potential of citrus medica
    Authors: Oyepata Simeon Joseph, Omoirri Aziakpono Moses, Adekunle Theophilus Adegbuyi, Opeyemi Tosin Joseph
    JOPAT (2026)
  4. Comparative Phytochemical Analysis of Citrus medica fruit juice and peels.
    Authors: Simeon, J. O., & Tosin, J. O
    Caliphate Journal of Science and Technology (2025)
  5. Comparative Phytochemical Analysis of Citrus medica fruit juice and peels
    Authors: Opeyemi JT, Oyepata JS, Sabastine ZA and Chukwuebuka OF
    Trop J Nat Prod Res. (2025)
  6. Effect of leaf extract and fractions of Solanum anomalumon oxidative stress markers,kidney function indices and histology of alloxan-induced diabetic rats.
    Authors: Etuk IC, Udobang JA, Daniel AO, Ekong O, Okokon JE, Joseph OS
    Journal of Current Biomedical Research. (2024)
  7. Evaluation of the phytochemical Constituent, acute toxicity and antiulcer activity of Duranta erecta fruit extracts. Journal of Herbs, Spices & Medicinal Plants,
    Authors: Joseph, O. S., Omoirri, M. A., & Joseph, O. T
    Journal of Herbs, Spices & Medicinal Plants (2024)
  8. Haematological, Renal and Gastric Effects of Ethanol Leaf Extract of Bauhinia variegate
    Authors: Oyepata JS and Adekunle AT
    Trop J Phytochem Pharm. Sci (2024)
  9. Antidiabetic activity of methanol leaf extract of Manihot esculenta crantz (cassava leaf) in alloxan induced diabetic mice: A Potential Alternative for Diabetes Mellitus treatment
    Authors: Omoirri MA, Oloche JJ, Nkechi JO, Amarachukwu UO, Ibeh CN, Jegi IF, Obi DM, Chukwunonso CO, Joseph OS, Adegbuyi, AT, Joseph OT, Zubairu SA
    Afr.J.Bio.Sc (2024)
  10. Sub-chronic Toxicological evaluation of extract of Lavandula stoechas on Liver, haematological parameters, and feed consumption of Wistar rats.
    Authors: Joseph OT, and Joseph OS
    Tanzania Journal of Health Research (2024)
  11. Toxicological Evaluation of Sub-Chronic Administration of Ethanol Leaf Extract of Ocimum canum on Lipid Parameters, Heart Histology and Feed Consumption of Wistar Rat
    Authors: Simeon, JO, Tosin JO
    Caliphate Journal of Science and Technology Journal/Caliphate Journal of Science and Technology (2024)
  12. Evaluation of synergistic cytotoxic potential of Zingiber officinale and Allium sativum on Wistar rats Testes
    Authors: Simeon JO, Tosin JO
    JOPAT (2024)
  13. Effect of Pterocarpus santalinus Ethanol Leaf Extract on Haematological, Histopathological and Lipid Profile Indices in Wistar Rats
    Authors: Oyepata JS, Opeyemi JT, Adekunle AT, Moses OA
    Trop J Nat Prod Res. (2024)
  14. Evaluation of Proliferative Potential of Musa Paradisiaca Stem Juice on the Pancreatic Cells of Wistar rats
    Authors: Oyepata JS and Opeyemi JT
    Trop J. Nat Prod Res (2024)
  15. Biochemical and Histological Evaluation of Sub-Chronic Administration of Canscora decussate Leaf Extract on Liver and Heart of Wistar Rats.
    Authors: Joseph OT, Joseph OS, Adegbuyi AT.
    Trop J. Phytochem Pharm. Sci (2024)
  16. Toxicological evaluation of ethanol leaf extract of Pterocarpus santalinus on lungs, stomach, brain and hematological parameters of Wistar rats
    Authors: Joseph, O. S., Joseph, O. T., El-Gazzar, A. M., Mahmoud, M. H., Omoirri, M. A., & Gaber, E. S. B
    Cogent Food & Agriculture, (2024)
  17. Nephroprotective effect of Anacardium occidentale (cashew) apple juice on kidney
    Authors: Simeon JO, Zubairu SA, Tosin JO
    Future Natural Products (2023)
  18. Evaluation of anti-ulcer activity of methanolic extract Combretum paniculatum Vent. in rats and mice using pylorus–ligation induced model.
    Authors: Builders MI, Udeh BO, Ede SO, Joseph SO, Ise PU.
    Open Access Research Journal of Life Sciences (2023)
  19. Evaluation of hepatoprotective activity of the aqueous extract of Vitisvinifera against acetaminophen-induced liver damage in rats.
    Authors: Builders M, Okoli IS, Ede SO, Joseph OS, Ise UP
    Magna Scientia Advanced Research and Reviews (2023)
  20. Evaluation of Anxiolytic Activity of Ethanolic Extract of Thymus vulgaris Leaves Using Elevated Plus Maze [EPM] Test
    Authors: Builders MI, Oyefeso RA, Ede SO, Joseph SO, Ise PU
    . Journal of Advancement in Pharmacology (2023)
  21. Characteristic Effect of Cashew Apple Extract of Anacardiumoccidentale on Liver of Gentamicin Induced Injury in Albino Rats.
    Authors: Simeon JO, Tosin JO, Zubairu SA
    J Tradit Med Clin Natur (2023)
  22. Evaluation of acute and subacute toxicity of the extract of allium cepa peels in Wistar rats.
    Authors: Builders MI, Michael GZ, Ede SO, Joseph SO, Ise PU
    World Journal of Advanced Research and Reviews (2023)
  23. Update report on progress of COVID-19 pandemic from 19th-25th January, 2022 across different countries of the world.
    Authors: Simeon, J.O., J.O. Tosin and S.A. Zubairu
    Asian J. Appl. Sci (2023)
  24. Evaluation of the Effect of Anacardium Occidentale Cashew Apple Juice on Kidney of Gentamicin Induced Injury in Albino Rats
    Authors: Joseph O. Simeon., Joseph O. Tosin., Sabastine A. Zubairu.
    Journal of Clinical and Laboratory Research. (2023)
  25. Evaluation of Anxiolytic Activity of Ethanolic Extract of Thymus vulgaris Leaves Using Elevated Plus Maze [EPM] Test
    Authors: Ise, U.P.,OyepataS.J ., Famojuro, T.I.,Johnson O.J ., Sebastine A. Z, Ibrahim, A.M1 ., Williams Ujah and Builders, M.I.
    J. Pharm. Sci. & Res. (2023)
  26. Evaluation of the Effect of Anacardium Occidentale Cashew Apple Juice on Kidney of Gentamicin Induced Injury in Albino Rats
    Authors: Joseph Oyepata Simeon, Joseph Opeyemi Tosin, Sabastine Aliyu Zubairu
    Journal of Clinical and Laboratory Research (2023)
  27. Genetic, demographic and virology study on active and mortality cases ofCOVID-19 across different countries of the world as at 12th October 17,2022.
    Authors: Tosin JO, Simeon JO,Zubairu SA
    J RNA Genomics (2023)
  28. Evaluation of anti-ulcer activity of methanolic extract Combretum paniculatum Vent. in rats and mice using pylorus–ligation induced model.
    Authors: Builders MI, Udeh BO, Ede SO, Joseph SO, Ise PU
    Open Access Research Journal of Life Sciences (2023)
  29. Toxicological studies of ethanol leaf extract of Lavandula stoechas on kidney of Wistar rat.
    Authors: Joseph OS, Joseph OT.
    Journal of Current Biomedical Research (2023)
  30. Toxicological study of ethanol extract of Lavandula stoechas on Liver of Wistar rat.
    Authors: Modupe BI, Simeon JO, Tosin JO
    International Journal of Advances in Engineering and Management (2022)
  31. Effect of caffeine on diazepam-induced sedation and hypnosis in Wister rat
    Authors: Simeon JO, Builders M, Tosin JO
    GSJ (2021)
  32. The Relative Global Consequences of Cumulative Distribution of Covid-19, Using the USA as Comparism Factor and Cumulative Covid -19 Data of 31st October 2021.
    Authors: Simeon JO, Tosin JO, Adegbenga AD
    International Journal of Multidisciplinary Research And Analysis (2021)
  33. Clinical evaluation of the potential benefits of taking Moringaoleifera on blood triglyceride and cholesterol level in patient taking Tenofovir/Lamivudine/Efavirenz (TLE) combination
    Authors: Simeon JO, Zubairu SA, Tosin JO
    Journal of Pharmaceutical Science & Research. (2021)
  34. Concomitant administration of ethanol leaf extract of Thymus vulgaris on Diazepam– induced Sedation and Hypnosis in Wister Rat.
    Authors: Simeon JO, Simeon JO, Zubairu SA, Adegbenga AD
    Journal of Nursing and Health Science (2021)
  35. Global Implication of Differential Impacts of Covid-19 on Different Countries Using the USA as A Comparism Factor
    Authors: Smeon JO, Zubairu SA, Tosin JO
    Nursing and Health Science (2021)
  36. Effect of Cashew apple juice (Anacardiumoccidentale L.) on Hematology and Spleen of Gentamicin Induced Injury in Albino Rats.
    Authors: Sabastine AZ , Joseph OS , Joseph OS, Famojuro TI, Olorunfemi AF
    Global Scientific Journal (2021)
  37. Effect of Anacardium occidentale Fruit Juice Extract on Haematological Parameters and Spleen of Paracetamol Induced Injury in Albino Rats.
    Authors: Zubairu SA, Festus OA, Simeon JO, Irabor I, Tosin JO
    Global Scientific Journal (2021)
  38. Effect of Clinical Study of Moringaoleifera on Body mass index, Low density lipoprotein and Triglyceride level in Patients on Tenofovir/lamivudine/efavirenz Combination Therapy.
    Authors: Joseph SO, Opeyemi JT
    Advanced Herbal Med (2021)
  39. Effect of the Demographic of Covid-19 on Different Countries; Using the USA for Comparism
    Authors: Joseph OS , Builders M , Joseph O T , Famojuro TI, Ogira JO, Moses FD, Musa TL
    International journal of multidisciplinary research and analysis. (2021)
  40. Effect of ethanol leaf extract of Terminalia chebula extract on kidney of wister rats
    Authors: Zubairu SA, Simeon JO, Tosin JO
    Global scientific Journal (2021)
  41. Antimalarial Drugs and COVID -19.
    Authors: Builders MI, Simeon JO, Ogundeko TO, Builders P
    Sumerianz Journal of Medical and Healthcare (2020)
  42. The Dynamics of Differential Impacts of COVID-19 on African Countries Compared to Other Parts of the World
    Authors: Simeon JO.,Lubo MT., Tosin JO. , Irabor I.
    International journal of multidisciplinary research and analysis. (2020)
  43. Effect of Caffeine on Diazepam - Induced Sedation and Hypnosis in Wister
    Authors: Joseph O. S., Builders M., Joseph O. T
    Global Scientific Journal (2020)
  44. A Survey of Wound Care Practices by Nurses in a Clinical Setting
    Authors: Builders M. I.,Joseph S.O.,Bassi PU.
    International Journal of Healthcare and Medical Sciences (2020)
  45. Toxicological Study of the Effect of Ethanol Leaf Extract of Pterocarpus santalinus Extract on Liver of Wister Rats
    Authors: 62. Haruna WC, Builders M, Simeon JO, Tosin JO
    Nigeria biomedical Science Journa (2020)
  46. Effect of ethanol leaf extract of cassia angustifoliaextract on heart and lipid profile of wister rats.
    Authors: Haruna WC, Simeon JO, Builders M, Tosin JO
    African Journal of Pharmaceutical Research & Development. (2020)
  47. Sub-acute toxicity study of ethanol leaf extract of Ocimum canum on the kidney of wistar rats.
    Authors: Joseph OS, Builders M, Joseph OT, Sabastine AZ, Musa Tl and Oyepata PJ
    African Journal of Pharmaceutical Research & Development (2019)
  48. Effectiveness of intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine against malaria in northern Nigeria
    Authors: Builder MI, Anzaku SA, Joseph SO
    International Journal of Recent Scientific Research (2019)
  49. Effect of Parkiabiglobosa extract on open skin woundhealing in dexamethasone- induced hyperglycaemia and histological assessment in rats
    Authors: Modupe IB, Oyepata SJ, Akpobome RV
    African Journal of Pharmacy and Pharmacology (2019)
  50. Effect of Citrus Limon Juice and Tamoxifen on the Tumour growth mass Indices, Cell Proliferation, Cell Viability and Cytogenetic (Mitotic Index) of Sprague Dawley Rats Induced MCF-7 Breast Cancer Cells
    Authors: Oyebadejo S. A, Joseph O. S, Adesite S. O and Omorilewa A.O
    World Journal of Pharmacy and Pharmaceutical Sciences (2019)
  51. Effect of Citrus Limon Juice and Tamoxifen on the Tumour growth mass Indices, Cell Proliferation, Cell Viability and Cytogenetic (Mitotic Index) of Sprague Dawley Rats Induced MCF-7 Breast Cancer Cells
    Authors: Oyebadejo S. A, Joseph O. S, Adesite S. O and Omorilewa A.O
    Saudi Journal of Biomedical Research (2019)
  52. Toxicity study of ethanol leaf extract of ocimum canum on heart and lipid profile of wister rats
    Authors: Joseph OS, Builders M, Joseph OT, Ariahu EC, Zubairu SA, Musa T, and Joseph OP
    International Journal of Current Advanced Research (2019)
  53. Histological study of effect of ethanol stem extracts of Homalium letestui in paracetamol induced injury in albino rat, using various staining techniques.
    Authors: Sabastine AZ, Musa TL, Joseph OS, Builders M, Joseph OT
    American Journal of Biomedical Science & Research (2019)
  54. Effect of administration ethanol leaf extract of terminaliachebula on liver of wister rat
    Authors: Simeon JO, Builders M, Haruna WC, Tosin JO, Zubairu SA, Lubo MT
    International Journal of Research and Scientific Innovation (2019)
  55. Clinical study on the effect of Moringaoleifera on serum level of glucose and tryglyceride in subjects taken tenofovir, lamivudine and efavirenz combination regimen.
    Authors: Tosin JO, Wolfe OA, Iyeopu SM, Simeon JO, Chinwe A, Lubo MT
    European Scientific Journal. (2019)
  56. Hepatoprotective activity of extract of Homalium Letestui stem against carbon tetrachloride-induced liver injury
    Authors: Joseph O. S., Jude E.O and Joseph O. T.
    Advance Herbal Medicine (2018)
  57. Hepatoprotective activity of ethanol stem extract of Homalium letestui against thioacetamide-induced liver injury
    Authors: Joseph O. S. and Joseph O. T.
    The Nigerian Journal of Pharmacy (2018)
  58. Evaluation of Anti-Diarrhoeal Activity of Different Bark Extracts of Faidherbia albida (Delile) A (Chav) in Albino Rats
    Authors: Timothy, S.Y, Wazis, C.H, Midala, T.A.S, Joseph, O.S, Sabastine ,A.Z, Nachanaa, T, & Oiza, F.D.
    BIMA JOURNAL OF SCIENCE AND TECHNOLOGY GOMBE (2017)
  59. Hepatoprotective activity of Homaliumletestui stem extract against paracetamol liver injury
    Authors: Okokon JE. O, Joseph OS.and Umoh EE
    Avicenna Journal of Phytomedicine. (2016)
  60. Nephroprotective activity of Homaliumletestui stem extract against paracetamol induced kidney injury
    Authors: Okokon JE., Joseph OS. And Umoh EE
    Journal of Experimental and Integrative Medicine (2016)
  61. Changes in serum electrolyte, creatinine and urea of fresh Citrus limon juice administered to growing rabbits (Oryctolaguscuniculus)
    Authors: Solomon, I.P, Oyebadejo, S.A., Ukpo E.M. and Joseph, O.S
    International Journal of Agricultural Science Research (2015)
  62. Effect of Fresh Citrus limon Juice on Liver Histomorphology of Growing Rabbits (Oryctolaguscuniculus).
    Authors: Solomon, I.P, Oyebadejo, S.A., Ukpo E.M. and Joseph, O.S
    Journal of Agriculture and Veterinary Sciences (2015)

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Undergraduate Project Supervision

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