Full Member
FUOYE Academic Staff Profile
Dr. Jude Akinyelu
Senior Lecturer
Department of Biochemistry, Faculty of Life Sciences
Area of Specialization: Nanobiotechnology, Phytomedicine, and AI-Driven Drug Discovery
Biography
Dr. Akinyelu Jude is a Senior Lecturer in the Department of Biochemistry at Federal University Oye-Ekiti. He obtained his PhD in Biochemistry from the University of KwaZulu-Natal, Durban, South Africa, where his doctoral research focused on the development of ligand-tagged polymeric and gold nanoparticles for targeted gene and drug delivery to selected cancer cells. He also holds an M.Sc. in Biochemistry from the University of Ibadan, Nigeria, and a B.Tech. (Hons) in Biochemistry from the Federal University of Technology, Akure, Nigeria.
His research interests span nanobiotechnology, phytomedicine, translational medicine, and computational drug discovery. Driven by a passion for continuous learning and innovation, he integrates bioinformatics and artificial intelligence with these disciplines to address pressing biomedical challenges and advance the development of innovative diagnostic and therapeutic solutions.
He has collaborated and continues to collaborate with researchers from Nigeria, South Africa, Egypt, Kenya, the United Kingdom, the United States of America, and Canada on a wide range of multidisciplinary research projects. These collaborations include ground-breaking studies on the targeted delivery of betulinic acid to cancer cell mitochondria using eco-friendly synthesized gold nanoparticles; the design and synthesis of biogenic silver and selenium nanoparticles with anticancer, antioxidant, antidiabetic, and anticholinesterase properties; the evaluation of oxaunomycin as a repurposed therapeutic candidate for cancer treatment; and investigations into the susceptibility of the SARS-CoV-2 spike glycoprotein and RNA-dependent RNA polymerase to mutational changes.
Dr. Akinyelu has authored and co-authored numerous scholarly publications, including scientific articles in reputable international peer-reviewed journals and conferences.
He is a recipient of the prestigious National Research Foundation-The World Academy of Science (NRF – TWAS) Renaissance Doctoral Scholarship, NRF-TWAS travel grant, and TETFund-supported research grant.
Research Interests
Nanobiotechnology
Phytomedicine and Natural Product Research
Translational Medicine
Bioinformatics for Computational Drug Discovery
Artificial Intelligence in Biomedical Research
Qualifications
| Degree | Institution | Year |
|---|---|---|
| PhD (Biochemistry) | University of KwaZulu-Natal, Durban, South Africa | 2019 |
| M.Sc. (Biochemistry) | University of Ibadan, Nigeria | 2015 |
| B.Tech. (Hons) (Biochemistry) | Federal University of Technology, Akure, Nigeria | 2010 |
Membership of Professional Bodies
Paper Presentation - Local
6th International Science Conference, Federal University Oye-Ekiti, Ekiti State, Nigeria
Paper Presentation - International
9th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT), Chicago IL, USA
3rd World Congress on Recent Advances in Nanotechnology (RAN), Budapest, Hungary
10th International Conference on Advances in Science, Engineering, Technology and Health Care (ASETH), Cape Town, South Africa
Postgraduate M.Sc Supervision
Phenol-rich Extracts from Senna alata Mitigate Cardiomyopathy in Diabetic Rats Via Modulation of Pyroptosis
Quercetin Mitigates Bisphenol A-Induced Hepatotoxicity In Rats Via Modulation of Oxidative Stress, Inflammation, and Ferroptosis
Selected Publications
Hepato-renal protection by ferulic acid in a type 2 diabetic rat model: in vivo and in silico insights into carbohydrate metabolism, REDOX balance, and inflammation modulation
Authors: Jude Akinyelu, Akinwunmi Oluwaseun Adeoye , Chika Ifeanyi Chukwuma , Toluwase Hezekiah Fatoki, Olufunbi Kehinde Adewumi, Ikenna Maximillian Odoh, Gift Racheal Ekun, Abidemi Sherifdeen Adeleke
Biotechnologia • 2025
Open publicationPhenolic-rich extract from Citrus sinensis leaves attenuates diabetic cardiomyopathy in male wistar rats by modulating oxidative stress, hyperlipidemia, and pyroptosis-related gene expression
Authors: Jude Akinyelu, Akinwunmi Oluwaseun Adeoye, Abiodun Aladetuyi, Omodele Ibraheem, Adaora Chinemelum Onodugo, Olapade Samuel Akinlolu, John Adeolu Falode, Olabisi Tajudeen Obafemi, Toluwase Hezekiah Fatoki
Food Chemistry Advances • 2025
Open publicationGreen Synthesis and Characterization of Selenium Nanoparticles from Khaya grandifoliola, and Assessment of their Antioxidant, Antidiabetic, Anticholinesterase, and Anticancer Potential
Authors: Jude Akinyelu, Akinwunmi Oluwaseun Adeoye, Londiwe Simphiwe Mbatha, Olakunle Oladimeji, Abiodun Aladetuyi, Omodele Ibraheem, Adaora Chinemelum Onodugo, Olapade Samuel Akinlolu
Nanochemistry Research • 2025
Open publicationEvaluation of the Antioxidant, Antidiabetic, and Anticholinesterase Potential of Biogenic Silver Nanoparticles from Khaya grandifoliola
Authors: Jude Akinyelu, Abiodun Aladetuyi, Londiwe Simphiwe Mbatha, Olakunle Oladimeji
Pharmaceutical Nanotechnology • 2023
Open publicationFolate-targeted doxorubicin delivery to breast and cervical cancer cells using a chitosan-gold nano-delivery system
Authors: Jude Akinyelu, Olakunle Oladimeji, Aliscia Daniels, Moganavelli Singh
Journal of Drug Delivery Science and Technology • 2022
Open publicationLactobionic acid-chitosan functionalised gold-coated poly(lactide-co-glycolide) nanoparticles for hepatocyte targeted gene delivery
Authors: Jude Akinyelu, Olakunle Oladimeji, Moganavelli Singh
Advances in Natural Sciences: Nanoscience and Nanotechnology • 2021
Open publication
